p-ANCA Vasculitis

Today marks the one-year anniversary of entering Allen Memorial Hospital for my illness. I had been coughing sputum with blood for about a week previous and was being treated for pneumonia. Finally I became bed-ridden for two days and it was apparent that the antibiotics weren't helping. I went to the ER and within 24 hours I was sedated and flown to St. Mary's in Grand Junction. Five days later I was tested positive for p-ANCA+ vasculitis. Only about 3 in 100,000 people have this condition.

What it is:
periferal-Anti Nuclear Cytoplasmic Antibody -- immune system attacks itself

Positive -- tested positive for p-ANCA

Vasculitis -- inflammatory destruction of blood vessels

with

Pulmonary -- lung

Hemorrhage -- heavy bleeding

In my case, the ANCA affected the large blood vessels in my lungs, but did not affect my kidneys. There is no known cause for this condition.


How I've been treated:
While I was hospitalized I was on and off too many drugs for me to keep track of. After I came home I was taking Predinsone (steriods) and Cytoxan (chemotherapy, which interferes with rapidly dividing cells that make antibodies), both immunosuppressive drugs to stop tissue destruction from attack by my antibodies. I took Bactrim to protect me from infections because my immune system is suppressed by the steriods and chemo. I see a nephrologist (kidney doctor) periodically to monitor my immune system to make sure it's not going haywire as my drug doses decrease. Kidney specialists tend to see more cases of vasculitis than lung doctors do, so this is why I'm under the care of a nephrologist.

What this means long-term:
Since I recovered from my hospitalization, I have been very active and suffer from no ill effects of this condition. If all goes well, I will be weaned off all medication soon. It is possible that I can have a recurrence, but this is improbable and can be treated quickly.